CDC suggested that two groups of people should be vaccinated with COVID-19 vaccine as soon as possible.

The online and offline supply of antipyretics and COVID-19 drugs is sufficient.

　　In the past few days, the reporter saw from the circle of friends that a small number of "small partners" exposed the test results of COVID-19 antigen and showed positive results. Can I buy COVID-19 drugs such as Pfizer Paxlovid and Azvudine online now? There is no infection, do you need to prepare medicine at home? Who needs COVID-19 vaccine? In the past few days, the reporter has written the latest situation of disease prevention and control through online pro-testing, visiting pharmacies and combing authoritative information.

　　Pro-test:

　　Doctors can buy COVID-19 medicine in medical e-commerce with valid prescriptions.

　　Can I buy COVID-19 drugs on the medical e-commerce platform? On the morning of May 8, the reporter searched for Ali Health, JD Health and Meituan to buy medicines, but the keywords "Pfizer Paxlovid" and "Azvudine" on the home page all showed no results. Subsequently, the reporter consulted the doctor of its Internet hospital in JD Health and proposed to buy Pfizer Paxlovid. The doctor said that at present, JD.COM’s official self-operated platform does not have this medicine, but it can be purchased through the platform’s cooperative pharmacies. It is understood that this partner is the flagship store of Guokang Medical Clinic. The reporter saw from the store’s page that at present, azvudine, Pfizer Paxlovid (Nimatvir Tablets/Ritonavir Tablets) and Monola Wei Capsules of Merck are all available for sale. However, according to the process shown on the page, it is an appointment service, which requires registration+diagnosis and treatment+prescription, so it can be regarded as a one-time service.

　　In terms of selling price, the prices of azivudine, Pfizer Nimatvir Tablets/Ritonavir Tablets and Rituorui (Monola Wei Capsule) of Merck are 299 yuan, 2,170 yuan and 1,825 yuan. The reporter noticed that some users left a comment on May 3rd: "Buy on the first day and deliver on the second day", and the photos uploaded in the comment showed that the production date of azvudine was January 2023 and the validity period was until January 2024.

　　The reporter bought drugs in Meituan and entered the "COVID-19 Free Clinic" search. When he entered the "fever clinic guidance desk" page, there were five kinds of COVID-19 drugs to buy, all of which were shown as prescription drugs, including Pfizer Paxlovid (combined packaging of Naimatvir tablets/ritonavir tablets), Leruiling, Xiannuoxin (combined packaging of Xiannuowei tablets/ritonavir tablets), Mindevio and Rituorui. According to the page, the above drugs are not open for retail sale, and only users with positive nucleic acid/antigen can consult online doctors with positive results. When the reporter tried to buy Pfizer Paxlovid, he had to fill in the basic information and upload the positive certificate of COVID-19 infection, otherwise he could not enter the next Internet doctor’s diagnosis prescription.

　　In terms of selling price, Pfizer Paxlovid shows 2170 yuan, which is the same as that of JD Health platform. For the other four models, the prices of Leruiling, Sanofin (combined packaging of Sanofibrate Tablets/Littori Tonavir Tablets), Mindevio and Lezhuorui are 698 yuan, 725 yuan, 725 yuan and 1499 yuan respectively.

　　The reporter tried to buy COVID-19 medicine in Ali Health Pharmacy, and asked the doctor for a fever. At the expense of 5 yuan, he hung up the number of a doctor in Ali Health Internet Hospital, simply stated his illness and said that he needed to prescribe Pfizer Paxlovid, and soon the doctor made a prescription. However, in addition to doctors’ prescriptions, the platform also needs to fill in personal ID cards and other related information. After the information is filled in, you can enter the payment page. Pfizer Paxlovid shows that the price is also 2170 yuan on Ali Health Platform. According to insiders, COVID-19 medicine is sold in pharmacies, and pharmaceutical e-commerce provides a way to find medicine.

　　As for ibuprofen sustained-release capsules, Lianhua Qingwen tablets, acetaminophen tablets, Ganmaoling granules, Yanyan tablets and other drugs, according to a number of medical e-commerce platforms, they are currently sold in stock and the goods are sufficient.

　　Offline, "We now have Paxlovid from Pfizer (referred to as drug P) and Monola Wei from Merck (referred to as drug M); Compared with the existing consumption, the supply is sufficient. At present, the number of users of drug P is significantly higher than that of drug M. " The reporter learned from Guangzhou Hejia Hospital that in terms of price, drug P is 1790 yuan/box, and drug M is 1500 yuan/box. These drugs are sold at zero price. At present, the people who use drug M are mainly patients who can’t or are inconvenient to use drug P, such as patients with poor liver and kidney function, or patients who are currently using a variety of drugs at the same time and will adjust the dosage and frequency of a large number of drugs because of taking drug P, which will increase the difficulty of monitoring.

　　Guangzhou United Family Hospital reminded that according to the process, Paxlovid from Pfizer and Monola Wei from Merck are both therapeutic drugs, and they need to be used only when COVID-19 is diagnosed. Therefore, the drug generally needs to be prescribed to patients who meet the drug instructions after the doctor’s diagnosis.

　　Inactivated vaccines and recombinant protein vaccines are in sufficient supply in the market.

　　"According to the recent monitoring of outpatients, the incidence of local influenza has shown a downward trend, while the infection situation in Covid-19 has increased slightly." Hu Dandan, director of the Children’s Health Department of Guangzhou Women and Children Medical Center, said this.

　　Last month, the Joint Prevention and Control Mechanism of the State Council issued the Work Plan for Vaccination in Response to the Recent Infection in Covid-19, which made it clear that the focus of vaccination in China at this stage is to fill the gap in immune level for different target groups and further reduce the risk of severe illness and death. Foshan CDC reminds that two groups of people who need to be vaccinated with COVID-19 vaccine as soon as possible include uninfected people who have not completed the established procedures and infected people who have not completed the basic immunization. The first group of uninfected people includes those aged 3-17 who are uninfected and have not completed the basic immunization, those aged over 18 who are uninfected and have not completed the first dose of booster immunization, and those aged over 18 who are uninfected and have not completed the second dose of booster immunization (high-risk people with infection, elderly people over 60 years old, people with serious basic diseases and people with low immunity). The second group of people who have been infected and have not completed basic immunization can be vaccinated with one dose after 3 months of infection.

　　It is understood that at present, inactivated vaccines (Zhongsheng, Kexing), recombinant protein vaccines (Zhifei, Livzon) and inhaled Kangxinuo adenovirus vector vaccines are relatively abundant in the market, and the disease control department suggests that qualified people can complete vaccination as soon as possible after meeting the time interval requirements.

　　Experts: Pay attention to vulnerable people and monitor early warning.

　　Covid-19 is back in the public eye again. What should we do? Zhang Wenhong, director of the Infectious Diseases Department of Huashan Hospital affiliated to Fudan University, said that to deal with the secondary infection in COVID-19, it is necessary to pay attention to vulnerable people, keep monitoring and early warning, prepare drugs well, and respond quickly to the arrival of any mutant strain.

　　Covid-19 infection treatment drugs are still welcoming "new stars". On March 28th, the quotation information of Shanghai Medical Insurance Bureau was publicized, and the treatment cost of Leruiling Lairuitewei tablets was 628 yuan per course, and it was included in the list of Class A drugs.

　　Up to now, there are six kinds of oral small molecule anti-COVID-19 drugs approved for marketing in China, including two imported drugs, Paxlovid (Nimatvir Tablets/Ritonavir Tablets) and Molnupiravir (Monola Wei Capsules), and four domestic drugs, namely azvudine, Mindevio, Senosin and Leruiling.

　　Li Ning, CEO of Junshi Bio, said earlier: "From the perspective of pharmaceutical manufacturers, the first thing we have to do is to be prepared. If there is infection, our drugs can meet the needs of patients "; Huaxin Securities Research Report believes that the demand for oral drugs in COVID-19 may reach a peak. In addition, the demand for COVID-19 drugs among people over 60 will remain at a high level.

Buprofen tablets production workshop

　　In the field of proprietary Chinese medicines, the reporter visited pharmacies and found that local "star drugs" such as Baiyunshan Banlangen granules, Kouyanqing granules, Baiyunshan antiviral oral liquid and Xiaochaihu granules were all placed in a conspicuous position. Guangzhou Pharmaceutical Group introduced Baiyunshan and Huangzhong Medicine. On the one hand, the daily production capacity of Baiyunshan Radix Isatidis granules and compound Radix Isatidis granules can reach 200,000 packs. On the other hand, consumers are more rational, and most of them are purchased in small batches, so the channel supply can basically be met; Baiyun Mountain Huacheng Pharmaceutical Co., Ltd. said that Baiyun Mountain antiviral oral liquid continued to sell well. The company had previously introduced a new production line to produce antiviral oral liquid, in order to increase production capacity to meet market demand.